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Factor XIII Deficiency

Factor XIII (13) deficiency is an inherited bleeding disorder caused when person’s body doesn’t produce enough of a protein in the blood (factor XIII or FXIII) which helps blood clot or the factor XIII doesn’t work properly. It is very rare, affecting approximately one in 1,000,000 people. Usually both parents have the gene alteration causing the disorder and have passed it onto their child. It affects both males and females.

Links to selected resources:

What Is Factor XIII Deficiency?
(World Federation of Hemophilia)
Explains the causes of this blood disorder, its symptoms, diagnosis and treatment.

Factor XIII deficiency
(Canadian Hemophilia Society, 2001)
Explains how factor XIII deficiency is passed on, what causes it, diagnosis, symptoms, treatments, preventing and treating bleeds, issues relating to women, pregnancy and fertility, lifestyle and vaccinations.

Factor XIII deficiency
(National Hemophilia Foundation, USA)

Source: What are rare clotting factor deficiencies? World Federation of Hemophilia, Montreal, Canada, 2023.

NB¬†We provide these links as a service to the haemophilia community. As web sites can change or should you find a site to be no longer active please¬†notify [email protected]. Haemophilia Foundation Australia is not responsible for the content of any external web sites. The featuring of a site on this page is not an endorsement by HFA of the information or views expressed therein.

Date last reviewed: 1 February 2024

Important Note: This information was developed by Haemophilia Foundation Australia for education and information purposes only and does not replace advice from a treating health professional. Always see your health care provider for assessment and advice about your individual health before taking action or relying on published information. This information may be printed or photocopied for educational purposes.

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